Annie Hsieh, MD, PhD is a physician-scientist in the Neuro-Oncology fellowship of Dana-Farber Cancer Institute and Massachusetts General Hospital. She obtained her MD from the Tzu Chi University in Taiwan and her PhD in Pathobiology from Johns Hopkins University under the mentorship of Dr. Chi V. Dang, where she co-discovered that the MYC oncogene could disrupt the circadian molecular clock, contributing to aberrant metabolism and cell growth. She also collaborated with neuroscientist Dr. Amita Sehgal and discovered that both upregulation and downregulation of Drosophila Myc affect circadian behavior and metabolism in fruit flies. Subsequently, she completed her Neurology residency at Albert Einstein Medical Center in Philadelphia, where she organized the first Neuro-Oncology tumor board. Currently, as a neuro-oncology fellow, she takes care of brain tumor patients at Mass General and conducts her research in the laboratories of Drs. Bernardo Sabatini and Marcia Haigis at the Harvard Medical School with support from the National Cancer Institute K12 program. Her research focuses on utilizing unbiased genomic CRISPR screen to identify novel regulators for glioma growth and investigating the metabolic regulations at the neuron-glioma synapses. Her goal is to have her own laboratory in the future to investigate how glioma takes advantage of the brain microenvironment and hijacks the metabolic pathways originally wired to produce neurotransmitters at the synapse.